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De sykdomsmodifiserende legemidlene brukes gjerne i kombinasjon med symptomlindrende legemidler som betennelsesdempende- og smertestillende legemidler.I en kommentar fra en pasientrepresentant i komitéen, Lucy Ryan, understrekes det at denne retningslinjen kan bidra til mer konsistens i behandlingen og støtten til personer med kronisk smerte.Det
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